High rate of anthropometric changes in adolescents predisposes them to future public health issues like obesity, cardiovascular diseases and musculoskeletal conditions. To mitigate these challenges there is need to improve anthropometric parameters through variable resistance training (VRT). This study was carried out to determine the effects of VRT on the anthropometric parameters; Body Weight (BW), Body Mass Index (BMI), Lean Body Weight (LBW), Percent Body Fat (%BF), Body Density (BD) and Thigh Circumference (TC) of early adolescents. The study adopted Specific Adaptation to Imposed Demands (SAID) principle. The pretest-posttest control group quasi experimental design was used. Early Adolescents of ages 10 to 15 who were not athletes but apparently sedentary students who preferred to engage in screen-based behaviour than engaging in exercise during leisure were purposively selected. These adolescents were selected from two Secondary Schools inOndo Municipality. Participants were randomly assigned to VRT and control groups.The treatment lasted for twelve (12) weeks. Data were analysed using Analysis of Covariance at .05 level of significance.There were significant main effects of treatment on the anthropometric parameters of BW (F(2,55)= 17.657;P<.05;η2=.243),LBW(F(2,55)=10.040;P<.05;η2=.154),%BF(F(2,55)=10.040;P<.05;η2=.156) and TC (F(2,55)=16.490;P<.05;η2=.231). The VRT was significant at improving anthropometric parameters; BW, BMI, LBW, BD and TC of early adolescents. Therefore, adolescents should engage in VRT for health benefits and improved quality of life regardless of gender. These trainings should be adopted since clinical impressions revealed that youth variable resistance training has the potential to offer observable health and fitness value to children and adolescents, provided that appropriate training guidelines are followed and qualified instructors are available.